ClutchPoints
Week 5 of the NFL season was a wild one, with crazy finishes and blown leads all over the league. Some of them came as a surprise, while others were just rhetorical latest episodes in futility for some of the NFL’s troubled franchises.
Who came out on the wrong end of Week 5? Let’s take a look at the biggest losers of the weekend.
The 2025 Arizona Cardinals are no stranger to confusing, heartbreaking losses. In fact, Jonathan Gannon’s group has already suffered a pair of them against divisional opponents. After squandering a chance to beat the 49ers on the road, the Cardinals lost a chance to complete a comeback against the Seahawks, losing both games on last-second field goals.
With a 21-6 lead over the winless Tennessee Titans and Emari Demercado strolling toward the end zone in the second half on Sunday afternoon, thoughts of a third such loss were nonexistent. However, a few seconds later, the Titans were right back in the game.
Cardinals RB Emari Demercado with a 72-yard touchdown run, but he dropped the ball before the goal line… pic.twitter.com/JPMm726fDO
— Arye Pulli (@AryePulliNFL) October 5, 2025
Tennessee scored a touchdown to cut the Arizona lead to 21-12, but the madness wasn’t done. With Tennessee driving in the fourth quarter and trying to get one of the two scores it needed, Cam Ward threw what should have been a game-ending interception. However, the Cardinals once again had other ideas.
Picked!
Fumbled!
Touchdown!A WILD @TITANS TD! pic.twitter.com/o22RMgaghL
— NFL (@NFL) October 5, 2025
Tennessee got the ball back again, and Ward hit Calvin Ridley down the sideline to set up a game-winning field goal. There are inexcusable losses every week in the NFL, and there were more on Sunday, but it will be hard to top this one in the foreseeable future.
Geno Smith had a stunning career resurgence with the Seattle Seahawks, turning himself into an above-average starter in the Pacific Northwest after spending most of his career as a backup. He played so well that he earned himself a big contract extension after a trade to the Las Vegas Raiders this offseason, and he lit up the New England Patriots in his Raiders debut in a Week 1 win.
Since that victory, the last month has been ugly. The Raiders lost their fourth straight game in a 40-6 rout at the hands of the Indianapolis Colts on Sunday, and Smith was a shell of the man that had the Seahawks, offensive line problems and all, on the verge of playoff contention every year.
Smith finished 25-for-36 with 228 yards and a pair of interceptions in this game, bringing his interception total to a league-leading nine in five games. His negative-0.30 EPA per dropback in Week 5 was the second-lowest of the week, beating out just Ravens backup...
