ClutchPoints
Last week was a massacre for bettors as true home teams went just 4-9 straight up on the weekend. Will this trend continue in Week 6? We’ll start to find out Thursday night, as the Philadelphia Eagles and New York Giants go at it in New Jersey. Until then, let’s dig into the ClutchPoints 2025 NFL Week 6 picks, predictions, and odds column.
In addition to the home teams’ futility in Week 5, the comebacks were crazy! The Tennessee Titans came back from an 18-point deficit to win, the Carolina Panthers from 17, the Denver Broncos and Jacksonville Jaguars from 14, the New Orleans Saints from 11, and the Commanders from 10.
And these comebacks mean that the games are coming down to the wire, which is fun for fans in general, but not the easiest to watch if you have some units on the games. In fact, this season there have been 17 games with a go-ahead score in the final minute of regulation, which is the most through five weeks in any season since the AFL-NFL merger in 1970.
The bye weeks continue in Week 6, as we bid adieu to the Houston Texans and Minnesota Vikings, while welcoming the Atlanta Falcons, Chicago Bears, Green Bay Packers, and Pittsburgh Steelers back to NFL action.
Here in Week 6, we’ll get a Thursday night game, a 9:30 a.m. ET matchup from London, England, seven 1:00 p.m. ET games, just three late window tilts, a Sunday night affair, and two Monday night showdowns, kicking at 7:15 p.m. ET and 8:15 p.m. ET.
This was a tough week with all the crazy comebacks and last-minute swings. For the first time this season, we were better against the spread (7-7) than picking straight up (4-10). So, that means on the season, we stay at .500 ATS with a 39-39 record, while we drop to 46-32 straight up.
Previous weeks: Week 1 | Week 2 | Week 3 | Week 4 | Week 5
So, let’s get right into the NFL Week 6 picks, predictions, and odds.
Courtesy of DraftKings, here are the NFL odds.
After a one-week Jaxson Dart bump, the Giants reverted to form and choked up a lead, losing to the lowly Saints. The Eagles lost, too, which led to some closed-door meetings in Philly, and those aren’t usually good.
Still, the Eagles have been good at rallying the troops and remembering that they have two incredible wide receivers whom they should get the ball to after a loss. That’s why, for at least one week, the Eagles will do the right thing, pump it to A.J. Brown and DeVonta Smith, and get an easy W
Pick: Eagles 28-13
One thing that a sinking ship doesn’t need is a trip across the Atlantic Ocean. That’s exactly what the Jets are doing, though, heading to Tottenham Stadium to take on the surging Broncos.
This game...
