ClutchPoints
Week 3 was an absolute rollercoaster ride. Can we expect more of that in Week 4? Well, we’ll start to get an idea on Thursday night, when the Seattle Seahawks and Arizona Cardinals do battle in an NFC West showdown. So, let’s dig into the ClutchPoints 2025 NFL Week 4 picks, predictions, and odds column.
Things were progressing nicely from a betting perspective in Week 3, right up until about 3:30 p.m. ET on Sunday. That’s when all hell broke loose. Picks were sixed, field goals blocked, and, to paraphrase the Red Zone’s Chris Hanson, wins became losses, and losses… well, they pretty much stayed losses.
But that’s OK. It’s the life of an NFL bettor, and we dust ourselves off, learn from our mistakes, and move on to the NFL Week 4 slate.
Here in Week 4, the schedule gets a little funky again as we enjoy the last weekend before bye weeks start. We’ll be treated to a Thursday night game, a 9:30 a.m. ET matchup from Dublin, Ireland, seven 1:00 p.m. ET games, four late window tilts, a Sunday night affair, and not one, but two Monday night showdowns.
As mentioned, Week 3 was a tough one here in the NFL Week 4 picks, predictions, and odds column. We were 7-9 straight up and 8-8 against the spread. That brings us to 32-16 straight up and 26-22 ATS on the season, so we’re still making money both ways!
Previous weeks: Week 1 | Week 2 | Week 3
So, let’s get right into the NFL Week 4 picks, predictions, and odds.
Courtesy of DraftKings, here are the NFL odds.
In the earliest weeks of this column, we talked about how we didn’t believe in the Cardinals this season, but we’d take them early because they started the campaign with the Saints and the Panthers. Now, after a loss to the Mac Jones-led 49ers, the Cards get another real team in the Seahawks, and that won’t go well.
The Seahawks can be a little scary, too, with Sam Darnold at the helm, but last week they took care of business when they should, trouncing the Saints 44-13. The transitive property doesn’t always work in sprots betting but give me the team that blew out the Saints over the team that only won by a touchdown.
Pick: Seahawks 16-13
International games are hard to predict, since no one knows how teams will react to the unorthodox travel and game schedules. The Steelers haven’t played abroad since 2013, though (a loss to Minnesota, ironically), while the Vikings have played outside the U.S. in 2024, 2022, and 2017.
The unknowns mean this game could be close, but with Carson Wentz’s steady (if unimpressive) hand leading the ship now and the purple defense getting after Aaron Rodgers, we’ll take the Vikes by at least a field goal in Ireland.
Pick: Vikings 24-20
**Philadelphia Eagles (-3.5) at Tampa Bay...
