NFL picks, predictions, odds for Week 3: Division matchups and a Backup Bowl

NFL picks, predictions, odds for Week 3: Division matchups and a Backup Bowl
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The 2025 NFL season is starting to settle in as Week 3 is now upon us. To kick off the festivities, we get an AFC East showdown between the Buffalo Bills and Miami Dolphins that the oddsmakers see as a blowout. Despite that, there is a solid slate ahead, so let’s jump right into the ClutchPoints 2025 NFL Week 3 picks, predictions, and odds column.

The more data points we have as bettors, the easier picking games becomes. Teams are starting to settle into their true identities, so it’s a little easier to figure out what a game will look like. That said, Vegas is full of high-rise casinos for a reason, and the line-setters are still incredible at what they do.

What you can start to count on is that the sharp bettors are still more locked in than the public, so fading the latter is a good strategy. If the percentage of money coming in on one side is opposite the percentage of bets made on the other, that’s a good sign the John Q. Bettor is about to take a bath.

Fading the public helped the NFL Week 3 picks, predictions, and odds column get to a winning record both straight up and against the spread after a quality Week 2.

In Week 3, we enjoy the most balanced slate we will see all year. We get the Thursday night matchup, nine early-window Sunday games, four in the late window, a Sunday night affair, and one Monday night showdown.

Week 2 got us back in action and over the summit of Mount .500. We only missed on two games straight up, going 14-2 picking winners. Against the number, we hit at a 69% clip, going 11-5 with the spread. That brings us to 25-7 straight up and 18-14 ATS on the season.

Previous weeks: Week 1 | Week 2

So, let’s get right into the NFL Week 3 picks, predictions, and odds.

Courtesy of DraftKings, here are the NFL odds.

Miami Dolphins at Buffalo Bills (-12.5)

Josh Allen and the Bills are a juggernaut right now after their thrilling Week 1 comeback and their 20-point trouncing of the Jets last week. With the horrible football we’ve seen out of the 0-2 Dolphins right now, there is no reason to think that Buffalo won’t win by at least two touchdowns here.

Pick: Bills 31-14

Las Vegas Raiders at Washington Commanders (-3.5)

Both of these teams looked disappointing in Week 2 after Week 1 wins. The Raiders beat the Patriots, then were outclassed by the Chargers, while the Commanders took care of the Giants easily before being taken care of with relative ease by the Packers.

This is still a game that the Commanders should win, but the Raiders have enough talent on the field to keep it close. The NFL Week 3 picks, predictions, and odds column will try to thread the needle on this one and take the Raiders if we can get the hook....