NFL picks, predictions, odds for Week 10:

NFL picks, predictions, odds for Week 10:
ClutchPoints ClutchPoints

As we crest the halfway point heading into Week 10, with the NFL trade deadline in the rearview mirror, the races for playoff spots and division titles are truly starting to shape up. Thursday night’s AFC West battle between the Denver Broncos and Las Vegas Raiders will figure into one of those races. Ahead of that, here is the ClutchPoints 2025 NFL Week 10 picks, predictions, and odds column.

After the favorites cruised to a 10-2 record in Week 9, Week 10 was a rough week of upsets and bad beats. The worst of all, was the Chicago Bears scoring a touchdown to win the game instead of kicking a field goal, which would have allowed the Cincinnati Bengals to cover.

Losses by Dallas Cowboys, Detroit Lions, and Indianapolis Colts were tough pills to swallow, too, as were way-too-close wins by the Los Angeles Chargers and Jacksonville Jaguars over the hapless Tennessee Titans and Raiders, respectively.

This week, we welcome back the four teams that sat out last week, which are the Cleveland Browns, New York Jets, Philadelphia Eagles, and Tampa Bay Buccaneers, and bid adieu to the Cincinnati Bengals, Dallas Cowboys, Kansas City Chiefs, and Tennessee Titans for a few days.

Here in Week 10, we get a Thursday night game, a 9:30 am ET kick from Berlin, Germany, seven 1:00 p.m. ET games, again just three late-window tilts, a Sunday night affair, and a single Monday night showdown.

It was a pretty brutal week here at the NFL Week 10 picks, predictions, and odds column. We still went 8-6 straight up, but with the spread, we were just 5-9 against the spread. This takes us to 79-56 straight up and 63-72 ATS on the season.

Previous weeks: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9

So, let’s get right into the NFL Week 10 picks, predictions, and odds.

Courtesy of DraftKings, here are the NFL odds.

Las Vegas Raiders at Denver Broncos (-9.5)

The Broncos come in as the way better team here at 7-2 to the Raiders’ 2-6 mark. It’s easy to see how this game could become a blowout quickly, which would be nice, so we could all get to bed earlier than expected tonight. However, there are a few signs that point to the Raiders making this a closer game than anticipated.

Las Vegas has Brock Bowers back now, which is a huge deal with his 12 catches for 127 yards and three touchdowns in Week 9. Also, the Broncos aren’t blowing most teams out. In their six-game win streak, they’ve beaten the Bengals and Cowboys by 20-plus, but their wins over the Eagles, Jets, Giants, and Texans are by a combined 10 points.

This is also a division game and a Thursday nighter, and we all know weird stuff happens in both those settings. So, while the Broncos will likely win here, we’ll take the...