NFL odds and picks 2025: Week 1 continues with Chiefs vs. Chargers in Brazil

NFL odds and picks 2025: Week 1 continues with Chiefs vs. Chargers in Brazil
The Phinsider The Phinsider

The first game of the 2025 NFL season is in the books, with the Philadelphia Eagles beating the Dallas Cowboys on Thursday night in the regular season opener. We did not have to wait long for the schedule to reach game two as the league continues their opening weekend with a Friday night game from Brazil.

The Kansas City Chiefs, the reigning AFC Champions, face their AFC West division rivals, the Los Angeles Chargers, in tonight’s game. Kickoff is set for 8 p.m. Eastern.

We continue our season-long picks pool for the contributors here on The Phinsider. All four of us made the correct straight-up winners picks for Thursday’s game. Now, we will look to improve to 2-0 on the season with tonight’s game.

Below you will find the odds for the game, the current standings for the group, and the picks for tonight. We are tracking the moneyline/straight-up winner pick for each contributor, but we have the ability to also pick against the spread and the point-total mark as well. You can check all of our picks below in the widget provided to us by Tallysight.

What are the latest odds?

Spread: Chiefs -3
Moneyline: Chiefs -172 | Chargers +144
Point Total: 47.5

Odds by FanDuel sportsbook.

2025 Standings

(Through Week 1 Thursday night)

James McKinney (1-0)
Marek Brave (1-0)
Sumeet Jena (1-0)
Kevin Nogle (1-0)

Chiefs vs. Chargers – Brazil