ClutchPoints
Running backs remain the heart of fantasy football. In Week 10 of the 2025 season, choosing the right one could be the difference between victory and heartbreak. With bye weeks hitting hard and injuries continuing to shuffle depth charts, fantasy managers are once again faced with tricky lineup decisions.
The Cowboys, Bengals, Titans, and Chiefs are on their bye. This means fantasy football lineups will miss key names like Javonte Williams, Chase Brown, and Isiah Pacheco. Meanwhile, teams like the Browns, Jets, Eagles, and Buccaneers return to action. They bring back names like Breece Hall and Rachaad White. Remember, though, that not all are great options this week.
Ahead of Week 10 of the 2025 NFL Season, it’s time to see which RBs to start and which ones to sit in your fantasy football team.
Kyle Monangai delivered a statement performance in Week 9. He rushed 26 times for 176 yards and caught three of five targets for 22 more in the Bears’ 47–42 shootout win over Cincinnati. With both D’Andre Swift (groin) and Roschon Johnson (back) sidelined, Monangai seized the opportunity. He exploded behind an improved offensive line. His 39-yard burst highlighted his blend of patience and power, proving he can handle a full workload.
Chicago may not rush either Swift or Johnson back with Monangai rolling. This is especially true with another soft matchup ahead against the Giants’ struggling run defense. Expect another high-volume RB2 performance with RB1 upside in Week 10.
It’s been a long road back for JK Dobbins. However, he finally looks like the explosive runner fantasy football managers remember. He’s averaging over five yards per carry this season, helping rejuvenate Denver’s backfield. The problem? His lack of passing-game involvement limits his weekly ceiling.
Still, game script is on his side this week. The Raiders rank in the bottom third of the league in rushing yards allowed per game. If the Broncos play with a lead, Dobbins could see 18+ carries. Yes, he’s touchdown-dependent. That said, everything about this matchup suggests a bounce-back performance. Pencil him in as a strong RB2 play with upside.
TreVeyon Henderson continues to gain traction in New England’s offense. Week 9 was another step forward. He logged 14 carries for 55 yards and caught four of six targets for 32 yards. With Rhamondre Stevenson (toe) sidelined, Henderson set career highs in carries and total touches.
Even if Stevenson returns, Henderson’s recent workload indicates he’s carved out a consistent role. Against a Buccaneers defense that’s been surprisingly generous to opposing backs, Henderson profiles as a flex-worthy play in PPR leagues.
Few running backs are as electric as De’Von Achane. He continues to thrive despite Miami’s offensive inconsistencies. In Week 9, he rushed 14 times for 67 yards and caught six of 10 targets for 39 more. His combination of burst and receiving usage keeps...
