Our weekly NFL defense rankings examine every unit across the league to determine the best defenses in the NFL. With the preseason wrapped up, let’s dive into our evaluations for the worst and best NFL defenses this season. We’ll update our NFL defense rankings, with analysis on all 32 teams, every Sunday night each week.
Our NFL defense ranks are updated as of Sunday, September 7, following the late-afternoon games in Week 1. You can find an analysis of all 32 defenses below our Week 2 fantasy defense rankings. You can also find a variety of NFL defensive stats further below, hiighlighting the best and worst defenses against the pass and run this season.
The following Week 2 defense rankings apply exclusively to this week, from a fantasy football perspective. The analysis of all 32 defenses season-long can be found further below.
Related: Week 2 Fantasy Rankings
As Bill Barnwell of ESPN noted after the trade, the Dallas Cowboys had the No. 1 defense in the NFL in EPA per play when Micah Parsons was on the field from 2021-’24. In Week 1, we saw glimpses of why the Green Bay Packers could have the best NFL defense in 2025 once Parsons gets up to speed.
Facing the highest-scoring team (33.2 PPG) in the NFL last season, Green Bay allowed the Detroit Lions to find the end zone just once. Parsons played a very limited snap count, but he still generated 1 sack, 1 TFL and 1 quarterback hit. The All-Pro edge rusher’s presence also opened things up for Rashan Gary (3 QB hits and 1.5 sacks) and Lukas Van Ness. Just a defensive clinic from Green Bay and Parsons is just getting warmed up. Jayden Daniels will prove far more elusive on Thursday Night Football in Week 2, but the Packers’ defense should still perform.
Related: NFL Week 2 Predictions
The Houston Texans defense delivered a performance worthy of a win in Week 1. Puka Nacua ([10-130...