Monday Night Football Week 5 Game Thread: Chiefs vs. Jaguars

Monday Night Football Week 5 Game Thread: Chiefs vs. Jaguars
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This evening, Monday Night Football brings week 5 to a close with a matchup that features a pair of AFC teams. Rarely are the Kansas City Chiefs entering a game with a worse record than their opponents, but that is the case this week as the 2-2 Chiefs visit the 3-1 Jacksonville Jaguars.

Jacksonville has a winning record largely because of their defense, a unit that leads the NFL in turnovers. They have forced at least three takeaways in each of their four games this season in an area that was a clear focus for new defensive coordinator Anthony Campanile — who was previously the Green Bay Packers’ linebackers coach.

Leading the Jaguars’ defense is a strong performance from linebacker Devin Lloyd, who has already matched his career-high with three interceptions. On the offensive side, running back Travis Etienne leads the NFL in rushing yards per game with just a shade under 100 through the first four weeks.

Then there are the Chiefs, who lost their first two games by a combined 9 points. Since then, they have bounced back with two straight wins, most recently a 37-20 victory over the Baltimore Ravens that saw Patrick Mahomes look like the Mahomes of old as he threw for four touchdowns and no interceptions.

Who will win tonight’s game and take a big step forward in the AFC’s early playoff race? Tune in to find out.

WHO?

Kansas City Chiefs (2-2) vs. Jacksonville Jaguars (3-1)

WHERE?

EverBank Stadium
Jacksonville, Florida

WHEN?

Monday, October 6, 2025
8:15 PM ET (7:15 PM CT)

HOW?

TV Broadcast

Channel: ESPN
Commentators: Joe Buck, Troy Aikman

Online Streaming

ESPN app, NFL app

WHAT ELSE?

Odds

Point Spread: Chiefs -3.5
Over/under total: 45.5

Last Meeting

Week 2 2023: Chiefs 17, @Jaguars 9