ClutchPoints
Twenty-eight teams will be active in Week 10 of the 2025 NFL season, leaving the same number of quarterbacks available for fantasy football managers.
Four teams go on bye in Week 10, forcing Patrick Mahomes, Dak Prescott, Joe Flacco and Cam Ward out of lineups. Ward has not been a fantasy-relevant player in year one, but Mahomes, Prescott and Flacco have all been top-10 options over the last month.
Jayden Daniels‘ fantasy owners are also forced to seek reinforcements with the second-year quarterback likely done for the year. Daniels will avoid surgery on his dislocated elbow, which gives him a chance to potentially return, but he will be out of commission for the foreseeable future.
With only 32 quarterbacks in play at one time, the position does not tend to be forgiving to desperate fantasy football managers. Yet, even in a week as chaotic as Week 10, there are a handful of overlooked players in favorable matchups worthy of streaming.
The San Francisco 49ers are confident that Brock Purdy can return soon, but it does not seem like Week 10 will be realistic. Fans can expect another start for Mac Jones, who might be an intriguing fantasy football quarterback play against the Los Angeles Rams.
The Rams will be the first team the 49ers rematch in 2025. Jones was spectacular in the first meeting, going 33-for-49 for 342 passing yards, two touchdowns and zero interceptions. He now has a chance to repeat that performance at home.
Jones’ big game against the Rams follows his season-long pattern of success against zone coverages. The former first-round pick has been substantially better against zone than he is against man. Los Angeles enters Week 10 deploying zone at the fifth-highest rate in the league, according to Pro Football Focus.
Jones’ lingering leg injuries could stir trouble against the Rams’ chaotic pass rush. However, he has been able to effectively neutralize pressure thus far, only taking more than two sacks in two of his seven games.
Bryce Young has not been an effective fantasy football quarterback thus far, which has led to his low ownership percentage in most leagues. He has busted in several previous favorable matchups, but he might have his best chance to perform in Week 10 against the New Orleans Saints.
Young led the Carolina Panthers to a shocking Week 9 victory over the Green Bay Packers, but he did so while managing just 107 scoreless passing yards. He now goes to the opposite end of the spectrum with a matchup against the New Orleans Saints, who enter Week 10 allowing the seventh-highest completion percentage and the eighth-most yards per pass.
Young has struggled all season, but he has been slightly better against zone coverages than he has against man. His best game of the season came in Week 2 against the Arizona Cardinals’ zone-dominant defense. The Saints enter Week 10 deploying zone at the 12th-highest rate in the league.
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