Quarterback Kyler Murray’s injury status has become one of the most discussed storylines around the Arizona Cardinals’ 2025 season. With the former No. 1 overall pick sidelined since early October due to a lingering foot injury, questions about his return both this season and beyond have been swirling.
Kyler Murray suffered a foot injury in Week 5 of the 2025 NFL season during a game against the Tennessee Titans. Despite efforts to return, the injury failed to progress as hoped through his recovery window.
On December 5, 2025, Cardinals head coach Jonathan Gannon officially announced that Murray will not return for the remainder of the 2025 season. Gannon explained that multiple medical evaluations, including a second opinion obtained out of state, showed the foot wasn’t healing sufficiently for Murray to play.
Gannon said:
“It wasn’t progressing in a way that we wanted, so we got another opinion… it’s just not right.”
— Head coach Jonathan Gannon on Murray’s injury outlook
This decision ended Murray’s season after just five games played.
With Murray sidelined and the Cardinals already struggling on the field, Arizona turned to backup quarterback Jacoby Brissett, who has started in Murray’s absence.
Cardinals coach Jonathan Gannon says QB Kyler Murray (foot) won't play again in 2025 season. pic.twitter.com/R1ZqjlVcTi
— NFL (@NFL) December 5, 2025
The Cardinals’ 2025 season now hinges on evaluating young players, reshaping depth charts, and preparing for the offseason.
No. Murray’s 2025 season is officially over. Despite being eligible to come off injured reserve after a three-week window, his foot injury did not improve enough for him to return to active status. The Cardinals evaluated his condition thoroughly before making that call, indicating that the organization prioritized Murray’s long-term health over a rushed comeback.
While Murray’s 2025 season ended early, his long-term future remains uncertain but hopeful. As of now:
Before the injury, Murray remained one of the NFL’s most dynamic dual-threat quarterbacks. Since being selected first overall by the Cardinals in 2019, he quickly became a defining offensive talent, earning accolades including NFL Offensive Rookie of the Year and Pro Bowl selections earlier in his career.
Q1. Is Kyler Murray playing again this season?
A. No. Cardinals coach Jonathan Gannon confirmed that Murray will not return for the remainder of the 2025 season due to a non-progressing foot injury.
Q2. What injury does Kyler Murray have?
A. Murray suffered a foot injury in Week 5 and was placed on injured reserve. His recovery...