Fantasy Football Wide Receiver Rankings: Week 5

Fantasy Football Wide Receiver Rankings: Week 5
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Week 5 of the fantasy football season is here. With it comes the first wave of bye weeks. The Bears, Falcons, Packers, and Steelers are all off. That leaves fantasy managers scrambling to fill wide receiver spots. That absence of depth raises the stakes at one of the most volatile positions in the game.

Wide receivers can dominate matchups one week and disappear the next. That’s thanks to injuries, defensive matchups, and even offensive line play impacting quarterback efficiency. This week’s rankings highlight both the perennial elite and the emerging threats forcing their way into weekly lineups. From Puka Nacua’s record-breaking pace to the reemergence of Davante Adams, managers will need to stay sharp and make bold lineup calls to survive the chaos.

Key Insights

One guy to keep tabs on is Quentin Johnston. He has broken out with consistent production through the first month. Emeka Egbuka, George Pickens, and Xavier Worthy also crack many top 15 rankings. Their performances validate the steady rise in usage.

Meanwhile, some big names have slipped. AJ Brown, Brian Thomas Jr, Jerry Jeudy, and Jameson Williams are all trending downward. That’s whether due to tough matchups, inconsistent play, or simply not commanding the target share fantasy managers expected. The wide receiver pool remains crowded, but knowing which trends to trust makes all the difference.

Here we will look at our NFL Fantasy Football Wide Receiver Rankings entering Week 5 of the 2025 regular season.

Week 5 Top Fantasy Football Picks – 2025

Amon-Ra St. Brown, DET (@ CIN)

If not for Puka Nacua’s historic start, Amon-Ra St. Brown would be the unquestioned headline at wide receiver this season. He has tallied six touchdowns in four games and the second-most receptions in the league. His consistency has just been unmatched. Now he gets a dream matchup against a Bengals defense that has been a sieve through the air. Detroit could dominate on the ground and still win this one easily. However, St. Brown’s route-running and chemistry with Jared Goff make him impossible to contain.

Justin Jefferson, MIN (@ CLE)

Jefferson is thriving even with Carson Wentz under center. Over the last two weeks, he’s averaged 11 targets, 10 receptions, and 126 yards per game. The touchdowns haven’t been there, sure. Still, the volume is elite. Week 5 brings a challenging matchup against Cleveland’s ferocious pass rush, with Myles Garrett capable of wrecking any offensive plan. Despite that, Jefferson is too talented and too heavily involved to ever bench. Managers should start him with confidence.

Emeke Egbuka, TB (@ SEA)

Egbuka’s start has been sensational. He sits sixth among wide receivers and ranks third in touchdowns at the position. His playmaking has given Baker Mayfield a reliable weapon. Egbuka also continues to command targets even with Chris Godwin back in the mix. The Seahawks defense will be his toughest test yet, though. They rank near the top in fewest receptions and yards allowed to wideouts. That said, Egbuka’s usage, red-zone role,...