ClutchPoints
The wait is over for fantasy football fans! Your favorite game is back, and Week 1 already brings tough decisions. Draft day excitement is behind us, rosters are set, and now managers face the real challenge: setting the right lineup. Few choices spark more second-guessing than quarterback. Do you lean on a proven veteran in a difficult matchup, or take a chance on a younger passer with upside? The difference between starting 1-0 and falling into an early hole often comes down to this one call. Let’s break down which quarterbacks you should confidently start and which ones you’re better off leaving on the bench as the 2025 season kicks off.
Ahead of Week 1 of the 2025 NFL Season, even after the Eagles already slipped past the Cowboys, it’s time to see which Quarterbacks to start and which ones to sit in your fantasy football team.
Kyler Murray enters the season healthy and motivated, and fantasy football managers should be optimistic about his opening matchup. The Cardinals are listed as six-point favorites against New Orleans, and Murray’s rushing ability makes him a must-start. Last season, he averaged 33.6 rushing yards per game. Three of the last five quarterbacks who faced the Saints topped 59 rushing yards, and Murray is far more dynamic than most. Even if game script limits his passing attempts, his legs give him one of the safest floors of any quarterback this week.
Josh Allen is an automatic start most weeks. However, Week 1 offers extra intrigue against the Ravens’ physical defense. Despite the tough matchup, Allen remains fantasy football gold. He was ranked the No. 1 quarterback for Week 1 by some pundits, thanks to his dual-threat ability and knack for putting the Bills on his back. In last year’s AFC Divisional Round win over Baltimore, Allen threw for just 127 yards but scored two rushing touchdowns. With Buffalo’s backfield options unproven, Allen will once again be tasked with carrying the offense. Expect high usage, rushing scores, and a big fantasy day.
If there’s a dream matchup for Week 1, Trevor Lawrence has it. Carolina allowed the most fantasy football points to opposing quarterbacks in 2024. They gave up 35 passing touchdowns and 40 total scores to the position. Lawrence now has his full arsenal intact, with rookie standout Travis Hunter healthy alongside Christian Kirk and Zay Jones. This will be the first home opener of Lawrence’s career. History suggests he thrives early. He has topped 21 fantasy points in two of his previous four openers. Given Carolina’s struggles, Lawrence has every opportunity to hit the over. Pencil him in as a strong starter with QB1 upside.
Other strong starts: Tua Tagovailoa, MIA (@ IND), Brock Purdy, SF (@ SEA).
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