ClutchPoints
We are four weeks into the 2025 NFL season, and with that, you are four weeks into your fantasy football season. Plenty of standout performances from key players, as well as goose eggs from highly-drafted players, has made this season tough to predict thus far.
The depth of your fantasy football roster is already being tested, as a plethora of star players have already missed time this season. All major offensive positions have been hit by injuries so far this season, as the quarterback (Joe Burrow), running back (James Conner), wide receiver (CeeDee Lamb), and tight end (George Kittle) spots have all had key players go down.
The following list includes players that are rostered on fewer than 50 percent of all ESPN rosters, making the chances you can pick them up decently high. Heading into Week 5, try your best to button up the edges of your roster as you look to rack up some victories.
The top name for your Week 5 waiver wire pickups is rookie running back Woody Marks, who had a Week 4 performance that solidified him as Houston’s top option. With Nick Chubb having held down the starting backfield job to start the year, Marks took hold of that in Week 4 and looks to be primed to fill that role for the rest of the season.
Every Week 3 touch for Woody Marks https://t.co/OLycsa9lvB pic.twitter.com/nrGi3QRfLj
— Jacob Gibbs (@jagibbs_23) September 22, 2025
Marks took 17 carries for 69 yards and a score, and caught four passes for 50 yards and another touchdown to put up an RB1 showing. As the Texans are still looking for a good offensive performance this year, Marks looks to be in line for an elevated workload moving forward.
Another week in the second spot in the waiver wire pickups for rookie wideout Elic Ayomanor, as he has solidified himself as the top WR in Tennessee. With the Titans struggling this year, they will be passing a ton in Cam Ward’s rookie season, and that will only help Ayomanor’s role on your fantasy football roster.
As the top wideout in the Week 5 waiver wire pickups, Ayomanor has earned five-plus targets in each of his first four games this season. Even with how inconsistent this TEN offense will be for fantasy football purposes, Ayomanor is probably the only pass catcher you can trust on a weekly basis for your flex spot.
It has been quite the surprising climb up the depth chart for Kendre Miller this year, as he has ascended from Dennis Miller’s dog house last season to earning quality snaps on offense. As the New Orleans Saints struggle through quarterback issues yet again, Miller has taken on a larger workload, even with Alvin Kamara still leading the way.
The likelihood of Kamara being traded to a...
