Fantasy Football: Top 10 waiver wire pickups for Week 16

Fantasy Football: Top 10 waiver wire pickups for Week 16
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If you are reading this article, then congratulations! You escaped the injury bug in the first round of the fantasy football playoffs, and you are one step closer to playing for a championship. The Week 16 NFL Power Rankings includes quite a few options to help plug some gaps in any of your rosters, as the likes of Davante Adams and Patrick Mahomes both suffered injuries this past week, with Mahomes now out for the rest of the season.

The following list includes players rostered on 50 percent or more of ESPN rosters, as this week’s list focuses on potential game winners rather than depth pieces. Heading into the first week of the playoffs, try your best to find that final missing piece your roster needs to win your opening-round matchup.

Week 16 Waiver Wire Pickups

1. RB Blake Corum, Los Angeles Rams
29.7% Rostered

The ascension of Blake Corum from infrequently-used backup to a guy who regularly earns double-digit touches has elevated this Los Angeles Rams offense to a new level this season, in turn providing your team with a FLEX option at running back.

Blake Corum is averaging 9.3 YPC over the last 3 weeks. No RB has more (min. 20 attempts).

He’s breaking out in real time. What a stud. pic.twitter.com/ldADD5ctLE

— Sosa Kremenjas (@QBsMVP) December 16, 2025

Corum has scored four touchdowns over the past three weeks, averaging 10 touches across that stretch of games, stepping into a sizable workload in Sean McVay’s offense. While Kyren Williams remains the lead back for the Rams, Corum should be the top target in your Week 16 waiver wire pickups, as he has entered RB2 territory.

2. RB Michael Carter, Arizona Cardinals
9.1% Rostered

With Bam Knight leaving Week 15 early with an injury, the Arizona Cardinals turned almost exclusively to Michael Carter to lead their backfield. His backfield workload shows that this Drew Petzing offense definitely trusts Carter to carry the load moving forward, something he should be asked to do again in Week 16.

A matchup with the Atlanta Falcons on deck in Week 16 gives Carter another chance to be a FLEX option for your lineups in round two of the fantasy football playoffs.

3. WR Jayden Reed, Green Bay Packers
45.9% Rostered

Jayden Reed has been heavily involved in the Green Bay offense the past two weeks, his first action since being injured in Week 2. Reed caught five passes for 55 yards in Week 15, a week after catching four passes and seeing two carries.

The injury to Christian Watson puts his status up in the air for Week 16, which would help elevate Reed into a larger role in the Green Bay offense. Look for Reed to jump into a larger role moving forward, even if Watson is healthy enough for next week.

4. TE Colby Parkinson, Los Angeles Rams
10.5% Rostered

The waiver-wire darling of Week 15 was tight end Colby Parkinson, who won quite a...