Colts bold predictions for blockbuster Week 12 clash against Chiefs

Few games on the Week 12 slate carry the same magnitude and urgency as Colts-Chiefs on the GEHA Field at Arrowhead Stadium. The Indianapolis Colts (8-2) arrive after a rejuvenating bye week. They enter playing the best football of any team in the AFC and boasting the league’s top scoring offense. Their surprising ascent under quarterback Daniel Jones and MVP frontrunner Jonathan Taylor has made them one of the NFL’s toughest outs. Meanwhile, the Kansas City Chiefs (5-5) are staring down the rare prospect of a lost season. That’s something virtually unthinkable in the Patrick Mahomes era.

Battle at Arrowhead

Indianapolis rolls into Kansas City with the swagger of a contender. They average 32.1 points per game and nearly 400 yards of offense. The Colts have built a dynamic, balanced attack behind Jones’ efficiency and Taylor’s takeover ability. Their offense excels at marrying play-action concepts with downhill power. Well, Kansas City happens to be one of the league’s worst defenses at handling exactly that combination. Coming off a bye, the Colts should be sharper, healthier, and more explosive as they attempt to take control of the AFC race.

Kansas City, meanwhile, is fighting for its life. The Chiefs enter on a two-game slide after losses to the Bills and Broncos. KC endured penalties, turnovers, and stalled drives in both contests. Mahomes has played at an MVP level but has been asked to compensate for an offense that lacks consistency. The Chiefs’ defense has been the bright spot this season. Even that unit, though, cracked against Denver and failed to pressure the quarterback. Playing at Arrowhead with their season in jeopardy, Kansas City must find answers quickly.

This is a desperation game for Kansas City and a validation game for Indianapolis.

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Here we will look at and discuss some bold predictions for the game between the Chiefs and the Colts in Week 12 of the 2025 NFL season.

Colts’ defense shuts down Patrick Mahomes

It feels quite bold to predict any team shutting down Mahomes. That said, if there was ever a week to expect it, this is the one. The Chiefs’ offense has been uncharacteristically sloppy, undermining Mahomes’ brilliance. The Colts, conversely, boast one of the NFL’s most disciplined defenses. They have allowed just 20.6 points per game and rank near the top of the league in quarterback pressure.

The midseason acquisition of Sauce Gardner has transformed Indianapolis’ secondary. Paired with a ferocious pass rush spearheaded by Laiatu Latu, the Colts suddenly have the personnel to disrupt Mahomes’ timing and force him into risky off-platform throws. Mahomes will commit multiple turnovers as the Colts dictate the pace defensively.

Jonathan Taylor rushes for over 150 yards

Very few teams have had an answer for Jonathan Taylor this season. Kansas City won’t be the exception. The Chiefs have quietly fielded one of the NFL’s leakiest run defenses. They have surrendered big totals multiple times this year. Against a...