ClutchPoints’ NFL Power Rankings, Week 6: Colts win as Bills, Eagles suffer first loss

ClutchPoints’ NFL Power Rankings, Week 6: Colts win as Bills, Eagles suffer first loss
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Week 5 of the 2025 NFL season was full of offensive firepower, as six teams scored at least 35 points this week. We have a new team atop the Week 6 NFL Power Rankings after both undefeated teams dropped their first games of the season.

Check out ClutchPoints’ Week 6 NFL Power Rankings to see where your team lands.

1. Detroit Lions (+2)

It took a 14-point third quarter to put things away, but the Detroit Lions made it four wins in a row after beating the Cincinnati Bengals, 37-24, moving up to the top spot in the Week 6 NFL Power Rankings. Their Week 5 win was mostly due to the passing attack and the defense, as Jared Goff threw four touchdowns and the defense racked up three interceptions.

You gotta love it!

In his return to his hometown where he played some QB in high school, Lions RB David Montgomery throws a TD pass!

: FOX pic.twitter.com/BiIp17hdvX

— FOX Sports: NFL (@NFLonFOX) October 5, 2025

Goff found Sam LaPorta, Jahmyr Gibbs, and Isaac TeSlaa for touchdowns, David Montgomery threw a short touchdown to Brock Wright, and the trio of Alex Anzalone, Amik Robertson, and Kerby Joseph each had an interception.

2. Tampa Bay Buccaneers (+3)

The cardiac Bucs are at it again, as the Tampa Bay Buccaneers earned their fourth win of the year on a fourth-quarter, game-winning drive. It was a fun offensive game for Tampa Bay to come out on the right side of, especially with how rookie Emeka Egbuka looked as Baker Mayfield’s top target, as the Buccaneers jumped up three spots in the Week 6 NFL Power Rankings.

The Ohio State rookie caught seven passes for 163 yards and a touchdown, hauling in a 57-yard deep ball from Mayfield that set up a short Rachaad White score. Stepping into the starting role with Bucky Irving’s injury, White ran for 42 yards and two scores and caught four passes for 30 yards as he stepped back into the role he held before Irving was drafted.

3. Buffalo Bills (-2)

In a weekend that saw the NFC’s lone undefeated team go down, the AFC lost its representative to that club, too, the Buffalo Bills. A home loss to the New England Patriots turns the AFC East on its head a bit, as the two-headed race becomes even tighter.

It was a quiet night for Josh Allen’s standards, as he threw for 253 yards and two scores, but a promising BUF drive ended on a costly Allen interception that would have minimally resulted in a field goal try.

4. Philadelphia Eagles (-2)

There are no more undefeated teams in the NFC after the upset home loss by the Philadelphia Eagles, as they dropped their Week 5 matchup to the Denver Broncos. After jumping out to a 17-3 lead, the Eagles defense allowed Denver to put up 18 unanswered points in the fourth quarter, resulting in PHI’s...