Revenge of the Birds
Are there must win games this early in the season? No, not in the NFL, unless you are 0-2 and could fall way behind in a competitive division.
No, instead you have a battle of two unbeaten teams, that are banged up, but both have the depth it seems to keep competing and keep putting themselves in positions to be successful.
Now, can the Arizona Cardinals find a way to play a complete game?
Update:
Here is everything you need to know about the Cardinals and 49ers game today.
Date: Sunday, September 21, 2025
Time: 1:25 p.m. AT
Location: Levi’s Stadium — Santa Clara, CA
National TV: Fox (Channel 10 locally)
National online streaming: NFL+, Fox Streaming
TV announcers: Adam Amin (play-by-play) Mark Sanchez (analyst) Kristina Pink (sideline)
Radio: Arizona Sports 98.7 FM
Radio announcers: Dave Pasch (play-by-play), A.Q. Shipley (analyst) and Paul Calvisi (sideline)
National Radio: ESPN Radio – Chris Carlin (play-by-play), Kelly Stouffer (analyst)
Spanish Radio: Fuego Radio 106.7 FM
Spanish Radio announcers: Luis Hernandez (play-by-play) and Irving Villanueva (analyst)
Betting line: Cardinals +2.5 per FanDuel Sportsbook
