Browns, 49ers report: Christian McCaffrey, Trent Williams, Denzel Ward do not practice Wednesday

The Cleveland Browns and San Francisco 49ers kicked off their practice week on Wednesday with Thanksgiving just a sleep away. The Browns have been struggling but are hoping QB Shedeur Sanders can help lift the offense and DE Myles Garrett can continue to dominate the competition, setting impressive numbers to start the 2025 NFL season.

Cleveland is hoping the schedule and a few other details could help them knock off the 8-4 visiting Niners in Week 13. As always this late in the season, health can play a big role in games.

Both teams had multiple players not practicing on Wednesday or limited in practice due to rest:

• RB Christian McCaffrey – DNP
• OT Trent Williams – DNP
• OG Joel Bitonio – Limited
• LB Devin Bush – Limited
• DT Maliek Collins – Limited
• S Grant Delpit – Limited
• S Ronnie Hickman – Limited
• DE Myles Garrett – Limited

It is interesting to see younger players like Bush, Delpit and Hickman getting rest for a three-win team.

The rest of the participation report with injuries was as follows:

Browns Injury Report

• TE Brenden Bates – Ankle – DNP
• CB Tyson Campbell – Hip – Limited
• RB Jerome Ford – Hamstring – Limited
• QB Dillon Gabriel – Concussion – Full
• DT Adin Huntington – Quad – DNP
• TE David Njoku – Knee – Limited
• LB Carson Schwesinger – Ankle – Limited
• WR Jamari Thrash – Foot – Limited
• DE Alex Wright – Quad – DNP
• CB Denzel Ward – Migraine – DNP

Given his history of head injuries, the Ward migraine issue is something to watch.

Niners Injury Report

• DE Robert Beal Jr. – Concussion – Full
• LB Tatum Bethune – Ankle – DNP
• LB Luke Gifford – Hip, calf – Limited
• DT Sam Okuayinonu – Ankle – DNP
• WR Ricky Pearsall – Knee – Full
• K Eddy Pineiro – Right hamstring – DNP
• OT Dominick Puni – Shoulder – Full
• QB Brock Purdy – Toe – Full

Reporting has noted that Okuayinonu is likely to head to IR.

With Thanksgiving on Thursday and the Niners on West Coast time, many will already be on to their seconds or thirds by the time the second injury report of Week 13 comes out.