Mile High Report
The offseason hype around the Denver Broncos is about to turn into regular season reality. Will they live up to that hype? We’ll start to find out during their Week 1 home game against the Tennessee Titans. As is typical of our weekly coverage, we’re giving our score predictions for this game.
Tennessee Titans at Denver Broncos
Sunday, September 7, 2025 at 2:05 P.M. Mile High time
Empower Field at Mile High in Denver, Colorado
ATS Betting Lines: Denver -8.5
Moneyline Odds: Denver -450 / Kansas City +350
Over/Under: 42.5
Note: All odds courtesy of FanDuel Sportsbook.
Collectively, our Mile High Report staff is predicting a Broncos 28-13 home win over the Titans in Week 1. We all predicted wins, but here is where we each landed individually on the score:
A strong start to the season is what this team needs. The schedule is a bit soft through the first ten games or so, but the back half of the schedule is quite brutal. They must start stacking wins early and often here and the Titans are not a team they should be struggling to beat at home if they are truly ready to contend in the AFC. Now is time to show you belong, Denver! – Tim Lynch
The Broncos begin their 2025 season against the team who performed the worst in 2024. I believe Titans quarterback Cam Ward will develop into a quality signal caller in the NFL. However, believe he will struggle going up against Denver’s defense which was the best at generating pressure last year. Rookie quarterbacks historically do terrible on the road in their debuts. Look for the Broncos’ defense to force multiple turnovers and help give the offense short fields to secure a victory in the season opener. – Chris Hart
Game one should be a chance for Sean Payton to send a message to the league. The Denver Broncos are here to dominate. The defense should be better than they were in 2024. The loss of Dre Greenlaw hurts, but this game should still be a big win. The reigning DPOY along with Nik Bonitto and company flying around is a scary proposition for the Titans offense. Expect Bo Nix to be unleashed. The run game will be better. This team is primed for a deep run in the playoffs and that all starts here. – Adam Malnati
I’m expecting the offense to look good, but it almost always takes time to get that side of the ball rolling come season. They’ll be solid, but also likely will leave points off of the board. They’ll defense, however, will be ready to fly around on Sunday. And while Cam Ward is the number one overall pick for a reason, this is a tall ask for a rookie QB in his first game. – Ross Allen
