Broncos vs. Jaguars betting odds for Week 16

Broncos vs. Jaguars betting odds for Week 16
Mile High Report Mile High Report

The Denver Broncos are now 12-2 and sit atop the AFC and in sole possession of that number one seed. They control their destiny and that destiny must start with another home win next week — this time over the Jacksonville Jaguars. Bo Nix is 14-2 at home in his career, with both of those losses coming early in his rookie season.

According to FanDuel, the Broncos are 3-point home favorites over the Jaguars in Week 16. The over/under stands at 44.5 for this matchup.

Broncos vs. Jaguars betting odds

Denver Broncos vs. Jacksonville Jaguars Sunday, December 21, 2025 at 2:05 P.M. Mile High time
Empower Field at Mile High in Denver, Colorado
ATS Betting Lines: Denver -3
Moneyline Odds: Denver -156 / Jacksonville +132
Over/Under: 44.5

I truly believe that the Green Bay Packers were the toughest opponent left on the Broncos schedule, but that is not to say the Jaguars are to be taken lightly. They have also been one of the hotter teams on offense and have been obliterating their opponents each and every week. Trevor Lawrence has been magnificent during their five game win streak too.

They have won by three or more scores in four of their last five games and have scored 25 or more points in each of their last seven. The Jaguars offense has been on fire. They will be a very good test for a Broncos defense that has been struggling at times over the last three games. Hopefully we see them shut down Lawrence and that Jags offense next week.

What are your predictions for the Broncos-Jags game in Week 16?