The Buffalo Bills are 4-0 for the first time since the 2020 NFL season, with wins against the Baltimore Ravens, New York Jets, Miami Dolphins, and most recently the New Orleans Saints. They’ll complete their first pass through the AFC East in Week 5, hosting the New England Patriots for the final matchup in their three-game homestand.
As one might expect of the 0nly undefeated AFC team, the Bills enter as heavy favorites over the 2-2 Patriots. As of publishing, FanDuel Sportsbook lists Buffalo as 8.5-point (-8.5) favorites over New England for their Week 5 date under the lights of Sunday Night Football.
Divisional games are usually difficult to gauge from a competitive standpoint simply because the teams know one another decently well, despite season-to-season roster turnover. When it comes to Bills-Patriots, there’s no love lost thanks to the long stretches of one-sided dominance. Now, with Mike Vrabel back in Foxborough as head coach and with the return of Josh McDaniels as offensive coordinator, there’s enough of the old New England brigade to renew this stalled rivalry.
The Patriots will be the first team Buffalo faces this season with at least one win to their name. Are the Bills up to the challenge, ready to hand a setback to quarterback Drake Maye and company? It’s likely to be an interesting game, and one oddsmakers have given the highest O/U total (50.5) in Week 5.
Buffalo needs to get things sorted out on defense and special teams such that they can hold the Patriots to a more reasonable points total than the 42 points they scored against the Carolina Panthers on Sunday. Similarly, the Bills need to get back to their early dominant ways, avoiding second- and third-quarter naps that keep them out of the end zone or scoring range altogether.
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