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The Buffalo Bills are entering Week 6 with something to prove. After rolling through the first month of the 2025 NFL season, Buffalo hit its first speed bump in a shocking 23-20 loss to the New England Patriots on Sunday night. It wasn’t just the upset that stung but the manner in which it happened. The Bills clawed back to tie the game at 20-20 late in the fourth quarter, only to watch the Patriots march downfield and drill a 52-yard field goal with 15 seconds remaining.
Now, the Bills (4-1) head to Mercedes-Benz Stadium to face the Atlanta Falcons (2-2) in a Week 6 showdown that could define how this team responds to adversity. Buffalo remains one of the AFC’s premier contenders, of course. However, this game presents a critical opportunity to reassert dominance. For all their offensive firepower, the Bills have shown moments of inconsistency. That’s something head coach Sean McDermott was quick to address after the loss.
“It’s a good reminder for us of how you really don’t want to play and don’t want to live that type of life,” McDermott said. “We have to stay on the details, stay disciplined, and stay urgent. It’s about finishing plays, taking care of the football, and making good decisions.”
After four straight wins to start the year, the Bills’ setback came as a surprise to many. But with Josh Allen under center, Buffalo has rarely dropped consecutive games in the McDermott era. The team’s offensive structure remains among the league’s most explosive. They have averaged nearly 30 points per game prior to Week 5. Still, Buffalo will need to correct its red-zone inefficiency and turnover issues if it hopes to avoid another close-call disappointment.
Meanwhile, the Falcons come into the matchup refreshed after their bye week. At 2-2, Atlanta remains capable of looking competitive one week and disjointed the next. Quarterback Michael Penix Jr has flashed big-play potential. That said, the offense continues to revolve around the ground game, averaging 136.5 rushing yards per outing. Head coach Raheem Morris will rely heavily on his running backs to control the tempo and limit Buffalo’s offensive possessions.
The environment will favor Atlanta, but history suggests the Bills rarely lose focus two games in a row. That makes them particularly dangerous heading into this matchup.
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Here we will look at and discuss some bold predictions for the game between the Bills and the Falcons in Week 6 of the 2025 NFL season.
When it comes to bounce-back performances, few quarterbacks in the NFL respond better than Josh Allen. Against New England, Allen completed 22 of 31 passes for 253 yards. He also had two touchdowns and one interception, while also rushing for 53 yards and a score. Despite throwing a costly late interception, Allen still displayed command, arm strength, and trademark improvisational flair.
Expect him to put up even...
