In a clash for NFC supremacy against the Tampa Bay Buccaneers, the San Francisco 49ers entered Sunday’s contest on the road shorthanded. With 23 players currently nursing injuries, the 49ers would need all hands on deck to defeat the Buccaneers. Unfortunately for the visitors, their vaunted defense sustained another big blow. Midway through the first quarter, star linebacker Fred Warner has left the game with a gruesome leg injury, per NFL insider Jordan Schultz on X, formerly Twitter.
Fred Warner was carted off in an air cast. Foot was turned sideways. pic.twitter.com/7CuMQJYEHq
— Jordan Schultz (@Schultz_Report) October 12, 2025
“Fred Warner was carted off in an air cast,” reported Schultz. “Foot was turned sideways. ”
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